Background The incidence of hematologic cancers increases with age. These cancers are
associated with recurrent somatic mutations in specific genes. We hypothesized that such …

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

The beautiful colours of many inorganic compounds, including minerals and gemstones, as
well as the mysterious cold light of luminescence emitted by these materials, have attracted …

Hormone-related cancers, namely breast, endometrium, ovary, prostate, testis, thyroid and
osteosarcoma, share a unique mechanism of carcinogenesis. Endogenous and exogenous …

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for ∼9…

Carcinogenesis research is increasingly focused on chemicals that are not genotoxic and
yet, at high doses, can induce cancer, apparently by increasing cell proliferation. We …

Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about risk …

The authors describe the design and implementation of a large multiethnic cohort established
to study diet and cancer in the United States. They detail the source of the subjects, …

A cohort of 18,244 mostly middle-aged (45-64 years) men residing in four small geographically
defined areas of Shanghai was accrued between January 1986 and September 1989. In …

Familial clustering studies indicate that breast cancer risk has a substantial genetic
component 1 , 2 , 3 . To identify new breast cancer risk variants, we genotyped approximately …