This study describes the first known model of bone cancer pain in the rat. Sprague–Dawley
rats receiving intra-tibial injections of syngeneic MRMT-1 rat mammary gland carcinoma cells …

Abstract Changes in phenotype or connectivity of primary afferent neurons following
peripheral nerve injury may contribute to the hyperalgesia and allodynia associated with …

… to a noxious pressure stimulus of ∼100 g) and tactile allodynia (hypersensitivity to a
normally non‐noxious pressure stimulus of ∼15–20 g), as measured by a reduction in paw …

… ramp of 2.5 g/sec for 20 sec (50-g cut-off) (27). Tactile allodynia in mice was assessed by
applying a series of von Frey filaments to the plantar surface of the hind paw (range 0.01–1.66 …

The excitation of nociceptive sensory neurons by ATP released in injured tissue is believed
to be mediated partly by P2X 3 receptors. Although an analysis of P2X 3 knock-out mice has …

We have localized cannabinoid receptor 2 protein in rat and mouse somatic sensory nervous
system, using an antibody that recognizes mouse cannabinoid receptor 2 . Little or no …

Previous studies have demonstrated that the metabotropic glutamate receptor subtype 5 (mGlu5
receptor) is expressed in the cell bodies of rat primary afferent neurones. We have …

… cut-off value was set at 250 g. Each paw was treated as an … von Frey hair stimulation up to
15 g. A positive response was … the 2, 6, 10 and 15 g von Frey hairs. The percentage response …

… These potent algogens preferentially activate bradykinin B2 and B1 G protein coupled … Male
Wistar rats (150–200 g) were deeply anaesthetized with sodium pentobarbitone (Sagatal, 60 …

… World Theatre Daniel Meyer-Dinkgrafe Who's Who in Contemporary Gay and Lesbian
History From World War II to the Present Day Robert Aldrich and Garry Wotherspoon …