COVID-19 and multiorgan response
S Zaim, JH Chong, V Sankaranarayanan… - Current problems in …, 2020 - Elsevier
Since the outbreak and rapid spread of COVID-19 starting late December 2019, it has been
apparent that disease prognosis has largely been influenced by multiorgan involvement. …
apparent that disease prognosis has largely been influenced by multiorgan involvement. …
[PDF][PDF] The genetic basis of Mendelian phenotypes: discoveries, challenges, and opportunities
JX Chong, KJ Buckingham, SN Jhangiani… - The American Journal of …, 2015 - cell.com
Discovering the genetic basis of a Mendelian phenotype establishes a causal link between
genotype and phenotype, making possible carrier and population screening and direct …
genotype and phenotype, making possible carrier and population screening and direct …
Metabolism and roles of stilbenes in plants
J Chong, A Poutaraud, P Hugueney - Plant science, 2009 - Elsevier
Stilbenes are a small family of plant secondary metabolites derived from the phenylpropanoid
pathway, and produced in a number of unrelated plant species. These compounds have …
pathway, and produced in a number of unrelated plant species. These compounds have …
Genome-wide atlas of gene expression in the adult mouse brain
…, L Chen, L Chen, TM Chen, M Chi Chin, J Chong… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …
promise new insights into the relationship between genes, brain and behaviour. The cellular …
An anatomically comprehensive atlas of the adult human brain transcriptome
…, PM Cartagena, MM Chakravarty, M Chapin, J Chong… - Nature, 2012 - nature.com
Neuroanatomically precise, genome-wide maps of transcript distributions are critical resources
to complement genomic sequence data and to correlate functional and genetic brain …
to complement genomic sequence data and to correlate functional and genetic brain …
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
Since its first release over a decade ago, the MetaboAnalyst web-based platform has become
widely used for comprehensive metabolomics data analysis and interpretation. Here we …
widely used for comprehensive metabolomics data analysis and interpretation. Here we …
[HTML][HTML] The mutational constraint spectrum quantified from variation in 141,456 humans
Genetic variants that inactivate protein-coding genes are a powerful source of information
about the phenotypic consequences of gene disruption: genes that are crucial for the function …
about the phenotypic consequences of gene disruption: genes that are crucial for the function …
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
We present a new update to MetaboAnalyst (version 4.0) for comprehensive metabolomic
data analysis, interpretation, and integration with other omics data. Since the last major update …
data analysis, interpretation, and integration with other omics data. Since the last major update …
Using MetaboAnalyst 4.0 for comprehensive and integrative metabolomics data analysis
… companion MetaboAnalystR (Chong & Xia, 2018; Chong, Yamamoto, & Xia, 2019) package
to enable more flexible and reproducible metabolomics data analysis and batch processing. …
to enable more flexible and reproducible metabolomics data analysis and batch processing. …
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin‐dependent kinases cdc2, cdk2 and cdk5
Cyclin‐dependent kinases (cdk) play an essential role in the intracellular control of the cell
division cycle (cdc). These kinases and their regulators are frequently deregulated in human …
division cycle (cdc). These kinases and their regulators are frequently deregulated in human …