In this article, the authors examine the underlying factors that drove the outsized performance
of the Yale University Endowment over the past two decades. With the aid of the …

Carbon dioxide (CO 2), methane (CH 4), and nitrous oxide (N 2 O) are powerful greenhouse
gasses driving global change. As global atmospheric concentrations of CO 2, CH 4, and N …

As one of the most successful institutional investors in the world, the investment strategy
and operating model of the Yale Endowment has been concerned and even followed by …

Surface plasmon enhanced illumination (SPEI) devices could be useful in multielectron
beam lithography systems to meet the roadmap requirements for mask-and direct write …

Background Interferon beta-1a and glatiramer acetate are commonly prescribed for
relapsing-remitting multiple sclerosis (RRMS), but no published randomised trials have directly …

Natalizumab is the first α4-integrin antagonist indicated for the treatment of relapsing
multiple sclerosis (MS). Natalizumab has been shown to delay the accumulation of physical …

Background: Since the commercial introduction of disease-modifying drugs (DMDs) for the
treatment of multiple sclerosis (MS), there have been numerous randomized placebo-…

Introduction of the immunomodulating agents interferon beta-1a, interferon beta-1b, and
glatiramer acetate has lead to significant improvements in the care of patients with multiple …

YKL-40 is a chitin-binding protein that is elevated in patients with various inflammatory
conditions associated with ongoing remodeling. We investigated whether the levels of YKL-40 …

Background: It is not known whether the currently available treatment regimen of interferon
beta-1b (IFN²-1b) 250 µg provides the maximum benefit possible in the treatment of relapsing-…