T helper cell type 1 (Th1) and 2 (Th2) are central to immune regulation. However, no stable
cell surface marker capable of distinguishing and separating these two subsets of CD4 + …

Interleukin (IL)-18 induces interferon (IFN)-γ synthesis and synergizes with IL-12 in T helper
type 1 (Th1) but not Th2 cell development. We report here that IL-18 receptor (IL-18R) is …

The proteome of normal male urine from a commercial pooled source has been examined
using direct liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). The entire …

We have previously reported that mice lacking inducible nitric oxide synthase (NOS2)
developed enhanced Th1 cell responses. We now investigated the mechanism by which NO …

We show that the strength of T-cell stimulation determines the capability of human CD4 + T
cells to become interleukin-17 (IL-17) producers. CD4 + T cells received either high- (THi) or …

Objective Tolerogenic dendritic cells (DCs) are antigen‐presenting cells with an
immunosuppressive function. They are a promising immunotherapeutic tool for the attenuation of …

The effects of smoking cigarettes with differing FTC nicotine deliveries on anxiety and EEG
activity were evaluated in 40 smokers who were compared with 40 non‐smokers, matched for …

The extent to which caffeine antagonizes alcohol-induced impairment of simulated automobile
driving at the current lowest legal American limit (0.08% BrAC) was the focus of this study. …

Autoimmune pathologies are caused by a breakdown in self-tolerance. Tolerogenic dendritic
cells (tolDC) are a promising immunotherapeutic tool for restoring self-tolerance in an …

Processing exogenous and endogenous proteins for presentation by major histocompatibility
complex (MHC) molecules to T cells is the defining function of antigen‐presenting cells (…