User profiles for K. M. McCarthy

Kerrigan McCarthy

- KM McCarthy - Verified email at nicd.ac.za - Cited by 2525

Kate McCarthy

- Verified email at teagasc.ie - Cited by 56

Occludin is a functional component of the tight junction

KM McCarthy, IB Skare, MC Stankewich… - Journal of cell …, 1996 - journals.biologists.com
Occludin’s role in mammalian tight junction activity was examined by ‘labeling’ the occludin
pool with immunologically detectable chick occludin. This was accomplished by first …

Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells

ASL Yu, KM McCarthy, SA Francis… - … of Physiology-Cell …, 2005 - journals.physiology.org
The function of occludin (Occ) in the tight junction is undefined. To gain insight into its role in
epithelial cell biology, occludin levels in Madin-Darby canine kidney II cells were …

[HTML][HTML] Herb species inclusion in grazing swards for dairy cows—A systematic review and meta-analysis

KM McCarthy, CG McAloon, MB Lynch, KM Pierce… - Journal of Dairy …, 2020 - Elsevier
A systematic review and meta-analysis were conducted to estimate the effect of herb species
on milk production and urinary nitrogen (UN) excretion from grazing dairy cows. Grazing …

[HTML][HTML] Xpert MTB/RIF versus sputum microscopy as the initial diagnostic test for tuberculosis: a cluster-randomised trial embedded in South African roll-out of Xpert …

…, WS Stevens, LD Mametja, KM McCarthy… - The Lancet Global …, 2015 - thelancet.com
Background In South Africa, sputum smear microscopy has been replaced with Xpert MTB/RIF
as the initial diagnostic test for tuberculosis. In a pragmatic parallel cluster-randomised …

[PDF][PDF] Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish

…, DL Marvin, M Ligorio, L Dershowitz, KM McCarthy… - Cell, 2019 - cell.com
Xenograft cell transplantation into immunodeficient mice has become the gold standard for
assessing pre-clinical efficacy of cancer drugs, yet direct visualization of single-cell …

Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells

KM McCarthy, SA Francis… - Journal of cell …, 2000 - journals.biologists.com
Occludin and 18 distinct members of the claudin family are tetra-span transmembrane
proteins that are localized in cell-specific tight junctions (TJs). A previous study showed that …

[HTML][HTML] Outbreak of listeriosis in South Africa associated with processed meat

J Thomas, N Govender, KM McCarthy… - … England Journal of …, 2020 - Mass Medical Soc
Background An outbreak of listeriosis was identified in South Africa in 2017. The source
was unknown. Methods We conducted epidemiologic, trace-back, and environmental …

Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma

…, R Clagg, KM McCarthy… - Proceedings of the …, 2014 - National Acad Sciences
Embryonal rhabdomyosarcoma (ERMS) is a common pediatric malignancy of muscle, with
relapse being the major clinical challenge. Self-renewing tumor-propagating cells (TPCs) …

Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia

KM McCarthy, Y Yoong, NE Simister - Journal of cell science, 2000 - journals.biologists.com
KM McCarthy, NE Simister and Z. Wu, unpublished observations). These data suggest that
the lower band is the high mannose form of FcRn usually found in the endoplasmic reticulum, …

Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma

…, SP Garcia, H Xi, D Do, AH Jin, TC Eng, KM McCarthy… - Nature cancer, 2022 - nature.com
Rhabdomyosarcoma (RMS) is a common childhood cancer that shares features with
developing skeletal muscle. Yet, the conservation of cellular hierarchy with human muscle …