As a stock market investor, one invests in a company's future prospects and earnings
potential. The premise is that over time the price of the asset will grow in value, compounding …

In many areas of the United States the battle against tuberculosis is being lost. Two major
markers of this failure are the increasing incidence of tuberculosis and the rising prevalence of …

Fukuyama congenital muscular dystrophy (FCMD), muscle–eye–brain disease (MEB), and
Walker–Warburg syndrome are congenital muscular dystrophies (CMDs) with associated …

Striated muscle-specific disruption of the dystroglycan (DAG1) gene results in loss of the
dystrophin-glycoprotein complex in differentiated muscle and a remarkably mild muscular …

Analysis of a nuclear family with three affected offspring identified an autosomal-recessive
form of spondyloepimetaphyseal dysplasia characterized by severe short stature and a …

Pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) are autosomal
dominant osteochondrodysplasias that result in mild to severe short-limb dwarfism and early-…

Dystroglycan is a central component of the dystrophin-glycoprotein complex implicated in the
pathogenesis of several neuromuscular diseases. Although dystroglycan is expressed by …

Background Guidelines recommend effective on-demand therapy for all individuals with
hereditary angioedema. We aimed to assess the novel oral plasma kallikrein inhibitor, …

This article starts with a summary of options theory to set the basis for the balance of a
discussion which relates to the uses to which one can put these options to work as an important …

Clustered regularly interspaced short palindromic repeat (CRISPR) has arisen as a frontrunner
for efficient genome engineering. However, the potentially broad therapeutic implications …