User profiles for Sarah J. Campbell

SJ Campbell

University of Southampton
Verified email at soton.ac.uk
Cited by 107

Detecting recent positive selection in the human genome from haplotype structure

…, GJ McDonald, HC Ackerman, SJ Campbell… - Nature, 2002 - nature.com
The ability to detect recent natural selection in the human population would have profound
implications for the study of human history and for medicine. Here, we introduce a framework …

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

…, C Aucan, S Segal, CE Moore, K Knox, SJ Campbell… - Nature …, 2007 - nature.com
Toll-like receptors (TLRs) and members of their signaling pathway are important in the
initiation of the innate immune response to a wide variety of pathogens 1 , 2 , 3 . The adaptor …

Vitamin D receptor polymorphisms and susceptibility to tuberculosis in West Africa: a case-control and family study

…, SJ Campbell, K Fielding, B Bah, J Sillah… - Journal of Infectious …, 2004 - academic.oup.com
Vitamin D receptor (VDR) gene polymorphisms have been implicated in susceptibility to
tuberculosis (TB), but reports have been inconsistent. We genotyped the VDR single-nucleotide …

Polymorphism within the interferon-γ/receptor complex is associated with pulmonary tuberculosis

GS Cooke, SJ Campbell, J Sillah… - American journal of …, 2006 - atsjournals.org
Rationale: Interferon-γ (IFN-γ) is of central interest in the study of tuberculosis. A number of
single-gene mutations have been identified in the IFN-γ signaling pathway that predispose to …

Association of a Polymorphism in the P2X7 Gene with Tuberculosis in a Gambian Population

CM Li, SJ Campbell, DS Kumararatne… - The Journal of …, 2002 - academic.oup.com
Adenosine triphosphate (ATP) ligation of P2X 7 receptors expressed on human macrophages
that are infected with mycobacteria induces cell death and subsequent loss of intracellular …

Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa

…, SJ Campbell, K Fielding, J Sillah… - Proceedings of the …, 2006 - National Acad Sciences
The sst1 locus has been identified in a mouse model to control resistance and susceptibility
of Mycobacterium tuberculosis infection. Subsequent studies have now identified Ipr1 (…

Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis

GS Cooke, SJ Campbell, S Bennett… - American journal of …, 2008 - atsjournals.org
Rationale: Tuberculosis remains a major cause of morbidity and mortality in the developing
world. A better understanding of the mechanisms of disease protection could allow novel …

Red fox viromes in urban and rural landscapes

SJ Campbell, W Ashley, M Gil-Fernandez… - Virus …, 2020 - academic.oup.com
The Red fox (Vulpes vulpes) has established large populations in Australia’s urban and
rural areas since its introduction following European settlement. The cryptic and highly …

Property A and CAT (0) cube complexes

J Brodzki, SJ Campbell, E Guentner, GA Niblo… - Journal of Functional …, 2009 - Elsevier
Property A is a non-equivariant analogue of amenability defined for metric spaces. Euclidean
spaces and trees are examples of spaces with Property A. Simultaneously generalising …

Interleukin-8 polymorphism is not associated with pulmonary tuberculosis in the gambia

…, SJ Campbell, K Fielding, J Sillah… - The Journal of …, 2004 - academic.oup.com
To the Editor—Ma et al.[1] described a well-designed study providing evidence of an association
between the 251 promoter polymorphism of interleukin (IL)–8 and clinical tuberculosis …